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Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs

The nucleotide transition G→A is known as a hypermutation due to its high prevalence in HIV-1 and other pathogens. However, the contribution of the G→A transition in the generation of drug resistance mutations is unknown. Our objective was to ascertain the rate of nucleotide substitutions in proteas...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Turner, Dan, Brenner, Bluma, Moisi, Daniela, Liang, Chen, Wainberg, Mark A
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The International AIDS Society 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804718/
https://ncbi.nlm.nih.gov/pubmed/19825125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2652-7-1-69
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