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Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis.

It has been proposed that atherosclerotic arteries produce less prostacyclin (PGI2) than nonatherosclerotic arteries do, thereby predisposing arteries to vasospasm and thrombosis in vivo. We reexamined this concept by measuring spontaneous as well as arachidonate-induced PGI2 biosynthesis in aortic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mehta, J L, Lawson, D, Mehta, P, Saldeen, T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3132716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4511
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