Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis.

It has been proposed that atherosclerotic arteries produce less prostacyclin (PGI2) than nonatherosclerotic arteries do, thereby predisposing arteries to vasospasm and thrombosis in vivo. We reexamined this concept by measuring spontaneous as well as arachidonate-induced PGI2 biosynthesis in aortic...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mehta, J L, Lawson, D, Mehta, P, Saldeen, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280460/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3132716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4511
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