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Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis.

It has been proposed that atherosclerotic arteries produce less prostacyclin (PGI2) than nonatherosclerotic arteries do, thereby predisposing arteries to vasospasm and thrombosis in vivo. We reexamined this concept by measuring spontaneous as well as arachidonate-induced PGI2 biosynthesis in aortic...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Mehta, J L, Lawson, D, Mehta, P, Saldeen, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1988
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3132716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4511
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