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Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.
A substantially enriched preparation of Alzheimer paired helical filaments (PHFs) has been used as a starting point for biochemical studies. Pronase treatment, which strips off adhering proteins, leaves a resistant core that is structurally intact. This has been used to raise a monoclonal antibody t...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1988
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3132715/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4506 |
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