Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.

Several degenerative diseases of the nervous system are characterized by the presence of neuronal inclusions. Most of these inclusions are made of abnormal filaments and share epitopes with cytoskeletal proteins. One of these inclusions, the neurofibrillary tangle of Alzheimer disease, has recently...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Manetto, V, Perry, G, Tabaton, M, Mulvihill, P, Fried, V A, Smith, H T, Gambetti, P, Autilio-Gambetti, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4501
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