Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.

Several degenerative diseases of the nervous system are characterized by the presence of neuronal inclusions. Most of these inclusions are made of abnormal filaments and share epitopes with cytoskeletal proteins. One of these inclusions, the neurofibrillary tangle of Alzheimer disease, has recently...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Manetto, V, Perry, G, Tabaton, M, Mulvihill, P, Fried, V A, Smith, H T, Gambetti, P, Autilio-Gambetti, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4501
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