Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.
Several degenerative diseases of the nervous system are characterized by the presence of neuronal inclusions. Most of these inclusions are made of abnormal filaments and share epitopes with cytoskeletal proteins. One of these inclusions, the neurofibrillary tangle of Alzheimer disease, has recently...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280458/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2837768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4501 |
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