The TC10–Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons

Axonal elongation is one of the hallmarks of neuronal polarization. This phenomenon requires axonal membrane growth by exocytosis of plasmalemmal precursor vesicles (PPVs) at the nerve growth cone, a process regulated by IGF-1 activation of the PI3K (phosphatidylinositol-3 kinase) pathway. Few detai...

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Main Authors: Dupraz, Sebastián, Grassi, Diego, Bernis, María Eugenia, Sosa, Lucas, Bisbal, Mariano, Gastaldi, Laura, Jausoro, Ignacio, Cáceres, Alfredo, Pfenninger, Karl H., Quiroga, Santiago
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804484/
https://ncbi.nlm.nih.gov/pubmed/19846717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3907-09.2009
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