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The TC10–Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons
Axonal elongation is one of the hallmarks of neuronal polarization. This phenomenon requires axonal membrane growth by exocytosis of plasmalemmal precursor vesicles (PPVs) at the nerve growth cone, a process regulated by IGF-1 activation of the PI3K (phosphatidylinositol-3 kinase) pathway. Few detai...
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Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Society for Neuroscience
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2804484/ https://ncbi.nlm.nih.gov/pubmed/19846717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3907-09.2009 |
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