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MAP1B Regulates Axonal Development by Modulating Rho-GTPase Rac1 Activity
Cultured neurons obtained from MAP1B-deficient mice have a delay in axon outgrowth and a reduced rate of axonal elongation compared with neurons from wild-type mice. Here we show that MAP1B deficiency results in a significant decrease in Rac1 and cdc42 activity and a significant increase in Rho acti...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954117/ https://ncbi.nlm.nih.gov/pubmed/20719958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-08-0709 |
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