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Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

Familial hypercholesterolemia is an inherited disease in humans that is caused by a defect in the receptor for low density lipoproteins (LDLR). The existence of an animal model for this disease, the Watanabe heritable hyperlipidemic (WHHL) rabbit, makes it an attractive candidate for developing new...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Wilson, J M, Johnston, D E, Jefferson, D M, Mulligan, R C
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 1988
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Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4421
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