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Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.
Familial hypercholesterolemia is an inherited disease in humans that is caused by a defect in the receptor for low density lipoproteins (LDLR). The existence of an animal model for this disease, the Watanabe heritable hyperlipidemic (WHHL) rabbit, makes it an attractive candidate for developing new...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1988
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454468/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4421 |
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