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Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

Familial hypercholesterolemia is an inherited disease in humans that is caused by a defect in the receptor for low density lipoproteins (LDLR). The existence of an animal model for this disease, the Watanabe heritable hyperlipidemic (WHHL) rabbit, makes it an attractive candidate for developing new...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wilson, J M, Johnston, D E, Jefferson, D M, Mulligan, R C
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1988
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2454468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4421
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