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Dissociation of Calmodulin-Target Peptide Complexes by the Lipid Mediator Sphingosylphosphorylcholine: IMPLICATIONS IN CALCIUM SIGNALING

Previously we have identified the lipid mediator sphingosylphosphorylcholine (SPC) as the first potentially endogenous inhibitor of the ubiquitous Ca(2+) sensor calmodulin (CaM) (Kovacs, E., and Liliom, K. (2008) Biochem. J. 410, 427–437). Here we give mechanistic insight into CaM inhibition by SPC,...

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Detalhes bibliográficos
Main Authors: Kovacs, Erika, Tóth, Judit, Vértessy, Beáta G., Liliom, Károly
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804338/
https://ncbi.nlm.nih.gov/pubmed/19910470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053116
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