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Actin Pedestal Formation by Enteropathogenic Escherichia coli Is Regulated by IQGAP1, Calcium, and Calmodulin

During infection, enteropathogenic Escherichia coli (EPEC) injects effector proteins into the host cell to manipulate the actin cytoskeleton and promote formation of actin pedestals. IQGAP1 is a multidomain protein that participates in numerous cellular functions, including Rac1/Cdc42 and Ca(2+)/cal...

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Detalhes bibliográficos
Main Authors: Brown, Matthew D., Bry, Lynn, Li, Zhigang, Sacks, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596374/
https://ncbi.nlm.nih.gov/pubmed/18809683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803477200
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