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Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 Receptor

GLP-1 (glucagon-like peptide-1) is an incretin released from intestinal L-cells in response to food intake. Activation of the GLP-1 receptor potentiates the synthesis and release of insulin from pancreatic β-cells in a glucose-dependent manner. The GLP-1 receptor belongs to class B of the G-protein-...

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Main Authors: Underwood, Christina Rye, Garibay, Patrick, Knudsen, Lotte Bjerre, Hastrup, Sven, Peters, Günther H., Rudolph, Rainer, Reedtz-Runge, Steffen
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804221/
https://ncbi.nlm.nih.gov/pubmed/19861722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033829
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