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Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity
1. Glucagon and glucagon-like peptide-1 (GLP-1) are homologous peptide hormones with important functions in glucose metabolism. The receptors for glucagon and GLP-1 are homologous family B G-protein coupled receptors. The GLP-1 receptor amino-terminal extracellular domain is a major determinant of g...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573731/ https://ncbi.nlm.nih.gov/pubmed/12642379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705120 |
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