Stability of glucagon-like peptide 1 and glucagon in human plasma

To investigate the stability of glucagon-like peptide 1 (GLP-1) and glucagon in plasma under short- and long-term storage conditions. Pooled human plasma (n=20), to which a dipeptidyl peptidase 4 (DPP4) inhibitor and aprotinin were added, was spiked with synthetic GLP-1 (intact, 7–36NH(2) as well as...

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Detalhes bibliográficos
Publicado no:Endocr Connect
Main Authors: Wewer Albrechtsen, Nicolai J, Bak, Monika J, Hartmann, Bolette, Christensen, Louise Wulff, Kuhre, Rune E, Deacon, Carolyn F, Holst, Jens J
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317691/
https://ncbi.nlm.nih.gov/pubmed/25596009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-14-0126
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