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Increased cAMP Levels Modulate Transforming Growth Factor-β/Smad-induced Expression of Extracellular Matrix Components and Other Key Fibroblast Effector Functions

cAMP is a key messenger of many hormones and neuropeptides, some of which modulate the composition of extracellular matrix. Treatment of human dermal fibroblasts with dibutyryl cyclic AMP and forskolin antagonized the inductive effects of transforming growth factor-β (TGF-β) on the expression of col...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Schiller, Meinhard, Dennler, Sylviane, Anderegg, Ulf, Kokot, Agatha, Simon, Jan C., Luger, Thomas A., Mauviel, Alain, Böhm, Markus
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804188/
https://ncbi.nlm.nih.gov/pubmed/19858184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.038620
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