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α5β1 Integrin Engagement Increases Large Conductance, Ca(2+)-activated K(+) Channel Current and Ca(2+) Sensitivity through c-src-mediated Channel Phosphorylation

Large conductance, calcium-activated K(+) (BK) channels are important regulators of cell excitability and recognized targets of intracellular kinases. BK channel modulation by tyrosine kinases, including focal adhesion kinase and c-src, suggests their potential involvement in integrin signaling. Rec...

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Bibliografske podrobnosti
Main Authors: Yang, Yan, Wu, Xin, Gui, Peichun, Wu, Jianbo, Sheng, Jian-Zhong, Ling, Shizhang, Braun, Andrew P., Davis, George E., Davis, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804158/
https://ncbi.nlm.nih.gov/pubmed/19887442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033506
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