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A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer.

The selective transcription of the Rat insulin 1 gene is mainly dependent on a beta-cell-specific enhancer element located in the 5' flanking DNA. In analogy to many other viral and cellular enhancers, the insulin enhancer has been shown to be of a mosaic structure and the cis-acting elements o...

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Detalhes bibliográficos
Main Authors: Ohlsson, H, Karlsson, O, Edlund, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC280400/
https://ncbi.nlm.nih.gov/pubmed/3288987
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