A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer.
The selective transcription of the Rat insulin 1 gene is mainly dependent on a beta-cell-specific enhancer element located in the 5' flanking DNA. In analogy to many other viral and cellular enhancers, the insulin enhancer has been shown to be of a mosaic structure and the cis-acting elements of imp...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3288987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4228 |
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