A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer.
The selective transcription of the Rat insulin 1 gene is mainly dependent on a beta-cell-specific enhancer element located in the 5' flanking DNA. In analogy to many other viral and cellular enhancers, the insulin enhancer has been shown to be of a mosaic structure and the cis-acting elements of imp...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1988
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3288987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4228 |
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