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A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer.

The selective transcription of the Rat insulin 1 gene is mainly dependent on a beta-cell-specific enhancer element located in the 5' flanking DNA. In analogy to many other viral and cellular enhancers, the insulin enhancer has been shown to be of a mosaic structure and the cis-acting elements o...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Ohlsson, H, Karlsson, O, Edlund, T
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1988
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3288987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.12.4228
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