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Activity of Artemether and Mefloquine against Juvenile and Adult Schistosoma mansoni in Athymic and Immunocompetent NMRI Mice

Immune effector mechanisms can enhance the activity of antischistosomal drugs. We examined the in vivo effect of single oral doses of the antimalarials artemether (400 mg/kg) and mefloquine (200 mg/kg), recently described to have promising antischistosomal properties, against juvenile and adult Schi...

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Bibliografiske detaljer
Main Authors: Keiser, Jennifer, Vargas, Mireille, Doenhoff, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Tropical Medicine and Hygiene 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803518/
https://ncbi.nlm.nih.gov/pubmed/20065004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2010.09-0461
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