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Pre-association of polynuclear platinum anticancer agents on a protein, human serum albumin. Implications for drug design
The interactions of polynuclear platinum complexes with human serum albumin were studied. The compounds examined were the “non-covalent” analogs of the trinuclear BBR3464 as well as the dinuclear spermidine-bridged compounds differing in only the presence or absence of a central -NH(2)-(+) (BBR3571...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803314/ https://ncbi.nlm.nih.gov/pubmed/17992278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b708433c |
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