Prevention of high-fat diet-induced muscular lipid accumulation in rats by α lipoic acid is not mediated by AMPK activation

Skeletal muscle triglyceride accumulation is associated with insulin resistance in obesity. Recently, it has been suggested that α lipoic acid (ALA) improves insulin sensitivity by lowering triglyceride accumulation in nonadipose tissues via activation of skeletal muscle AMP-activated protein kinase...

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Main Authors: Timmers, Silvie, de Vogel-van den Bosch, Johan, Towler, Mhairi C., Schaart, Gert, Moonen-Kornips, Esther, Mensink, Ronald P., Hesselink, Matthijs K., Hardie, D. Grahame, Schrauwen, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803237/
https://ncbi.nlm.nih.gov/pubmed/19690335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M000992
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