Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

OBJECTIVE: Mitochondrial dysfunction and fat accumulation in skeletal muscle (increased intramyocellular lipid [IMCL]) have been linked to development of type 2 diabetes. We examined whether exercise training could restore mitochondrial function and insulin sensitivity in patients with type 2 diabet...

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Autors principals: Meex, Ruth C.R., Schrauwen-Hinderling, Vera B., Moonen-Kornips, Esther, Schaart, Gert, Mensink, Marco, Phielix, Esther, van de Weijer, Tineke, Sels, Jean-Pierre, Schrauwen, Patrick, Hesselink, Matthijs K.C.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828651/
https://ncbi.nlm.nih.gov/pubmed/20028948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1322
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