ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity

AIMS/HYPOTHESIS: Dissipating energy via mitochondrial uncoupling has been suggested to contribute to enhanced insulin sensitivity. We hypothesised that skeletal muscle mitochondria of endurance-trained athletes have increased sensitivity for fatty acid (FA)-induced uncoupling, which is driven by the...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Sparks, Lauren M., Gemmink, Anne, Phielix, Esther, Bosma, Madeleen, Schaart, Gert, Moonen-Kornips, Esther, Jörgensen, Johanna A., Nascimento, Emmani B. M., Hesselink, Matthijs K. C., Schrauwen, Patrick, Hoeks, Joris
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826430/
https://ncbi.nlm.nih.gov/pubmed/26886198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-3885-8
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