Structural requirements for peptidic antagonists of the corticotropin-releasing factor receptor (CRFR): Development of CRFR2β-selective antisauvagine-30

Different truncated and conformationally constrained analogs of corticotropin-releasing factor (CRF) were synthesized on the basis of the amino acid sequences of human/rat CRF (h/rCRF), ovine CRF (oCRF), rat urocortin (rUcn), or sauvagine (Svg) and tested for their ability to displace [(125)I-Tyr(0)...

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Detalhes bibliográficos
Main Authors: Rühmann, Andreas, Bonk, Ines, Lin, Chijen R., Rosenfeld, Michael G., Spiess, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC28031/
https://ncbi.nlm.nih.gov/pubmed/9860957
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