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Extension of Drosophila melanogaster lifespan with a GPCR peptide inhibitor
G protein-coupled receptors (GPCRs) mediate signaling from extracellular ligands to intracellular signal transduction proteins1. Methuselah (Mth) is a class B (secretin-like) GPCR, a family typified by their large, ligand-binding, N-terminal extracellular domains2. Down-regulation of mth increases t...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803097/ https://ncbi.nlm.nih.gov/pubmed/17546039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.2 |
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