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T cell intrinsic role of Nod2 in promoting type I immunity against Toxoplasma gondii
Nod2 belongs to the (NOD)-like receptor (NLR) family of proteins, which function as intracellular pathogen sensors in innate immune cells. Nod2-deficiency results in an impaired immune response against bacterial pathogens. However, our understanding of how this protein promotes host defense against...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803073/ https://ncbi.nlm.nih.gov/pubmed/19881508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1816 |
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