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T cell intrinsic role of Nod2 in promoting type I immunity against Toxoplasma gondii

Nod2 belongs to the (NOD)-like receptor (NLR) family of proteins, which function as intracellular pathogen sensors in innate immune cells. Nod2-deficiency results in an impaired immune response against bacterial pathogens. However, our understanding of how this protein promotes host defense against...

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Detalhes bibliográficos
Main Authors: Shaw, Michael H., Reimer, Thornik, Sánchez-Valdepeñas, Carmen, Warner, Neil, Kim, Yun-Gi, Fresno, Manuel, Nuñez, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803073/
https://ncbi.nlm.nih.gov/pubmed/19881508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1816
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