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NOD-like Receptors (NLRs): Bona Fide Intracellular Microbial Sensors

The NLR (nucleotide-binding domain leucine-rich repeat containing) family of proteins has been demonstrated to function as regulators of innate immune response against microbial pathogens. Stimulation of NOD1 and NOD2, two prototypic NLRs, results in the activation of MAPK and NF-κB. On the other ha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shaw, Michael H., Reimer, Thornik, Kim, Yun-Gi, Nuñez, Gabriel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572576/
https://ncbi.nlm.nih.gov/pubmed/18585455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.06.001
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