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NOD-like Receptors (NLRs): Bona Fide Intracellular Microbial Sensors
The NLR (nucleotide-binding domain leucine-rich repeat containing) family of proteins has been demonstrated to function as regulators of innate immune response against microbial pathogens. Stimulation of NOD1 and NOD2, two prototypic NLRs, results in the activation of MAPK and NF-κB. On the other ha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2572576/ https://ncbi.nlm.nih.gov/pubmed/18585455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.06.001 |
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