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Characterization of Genome Integrity for Oversized Recombinant AAV Vector
Application of recombinant adeno-associated virus (rAAV) in gene therapy has been limited by its packaging capacity. Recent studies suggested that rAAV could achieve persistent transgene expression beyond 4.7-kb packaging limit. To clarify the mechanism leading to transgene expression from oversized...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2803017/ https://ncbi.nlm.nih.gov/pubmed/19904236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.258 |
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