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A receptor model for tumor promoters: rational superposition of teleocidins and phorbol esters.

Four 12-O-tetradecanoyl-13-O-acetylphorbol-type tumor promoters--teleocidin, phorbol ester, aplysiatoxin, and ingenol ester--are superposed in an attempt to understand their common biological activity on the assumption that they may bind to the same receptor site. A method using three-dimensional co...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Itai, A, Kato, Y, Tomioka, N, Iitaka, Y, Endo, Y, Hasegawa, M, Shudo, K, Fujiki, H, Sakai, S
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3131760/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.11.3688
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