ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells.
Resistance of human cancer cells to multiple cytotoxic hydrophobic agents (multidrug resistance) is due to overexpression of the "MDR1" gene, whose product is the plasma membrane P-glycoprotein. Plasma membrane vesicles partially purified from multidrug-resistant human KB carcinoma cells, but not fr...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1988
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280257/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3368466/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.10.3580 |
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