Pharmacological Characterization of Human Incretin Receptor Missense Variants

Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are gut-derived incretin hormones that regulate blood glucose levels. In addition to their widely accepted insulinotropic role, there is evidence that GLP-1 modulates feeding behavior and GIP regulates lipid metab...

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Main Authors: Fortin, Jean-Philippe, Schroeder, Jonathan C., Zhu, Yuantee, Beinborn, Martin, Kopin, Alan S.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2010
Teme:
Metabolism, Transport, and Pharmacogenomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802486/
https://ncbi.nlm.nih.gov/pubmed/19841474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.160531
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