REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy

The REV3L gene, encoding the catalytic subunit of human polymerase ζ, plays a significant role in the cytotoxicity, mutagenicity, and chemoresistance of certain tumors. However, the role of REV3L in regulating the sensitivity of glioma cells to chemotherapy remains unknown. In this study, we investi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wang, Huibo, Zhang, Shu-Yu, Wang, Shuai, Lu, Juan, Wu, Wenting, Weng, Lin, Chen, Dan, Zhang, Yu, Lu, Zhipeng, Yang, Jingmin, Chen, Yuanyuan, Zhang, Xu, Chen, Xiaofeng, Xi, Caihua, Lu, Daru, Zhao, Shiguang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Duke University Press 2009
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802399/
https://ncbi.nlm.nih.gov/pubmed/19289490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-015
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi