REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy

The REV3L gene, encoding the catalytic subunit of human polymerase ζ, plays a significant role in the cytotoxicity, mutagenicity, and chemoresistance of certain tumors. However, the role of REV3L in regulating the sensitivity of glioma cells to chemotherapy remains unknown. In this study, we investi...

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Detalhes bibliográficos
Main Authors: Wang, Huibo, Zhang, Shu-Yu, Wang, Shuai, Lu, Juan, Wu, Wenting, Weng, Lin, Chen, Dan, Zhang, Yu, Lu, Zhipeng, Yang, Jingmin, Chen, Yuanyuan, Zhang, Xu, Chen, Xiaofeng, Xi, Caihua, Lu, Daru, Zhao, Shiguang
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2009
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802399/
https://ncbi.nlm.nih.gov/pubmed/19289490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-015
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