REV3L confers chemoresistance to cisplatin in human gliomas: The potential of its RNAi for synergistic therapy

The REV3L gene, encoding the catalytic subunit of human polymerase ζ, plays a significant role in the cytotoxicity, mutagenicity, and chemoresistance of certain tumors. However, the role of REV3L in regulating the sensitivity of glioma cells to chemotherapy remains unknown. In this study, we investi...

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Huvudupphovsmän: Wang, Huibo, Zhang, Shu-Yu, Wang, Shuai, Lu, Juan, Wu, Wenting, Weng, Lin, Chen, Dan, Zhang, Yu, Lu, Zhipeng, Yang, Jingmin, Chen, Yuanyuan, Zhang, Xu, Chen, Xiaofeng, Xi, Caihua, Lu, Daru, Zhao, Shiguang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Duke University Press 2009
Ämnen:
Basic and Translational Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802399/
https://ncbi.nlm.nih.gov/pubmed/19289490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2009-015
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