Surviving Hilar Somatostatin Interneurons Enlarge, Sprout Axons, and Form New Synapses with Granule Cells in a Mouse Model of Temporal Lobe Epilepsy

In temporal lobe epilepsy, seizures initiate in or near the hippocampus, which frequently displays loss of neurons, including inhibitory interneurons. It is unclear whether surviving interneurons function normally, are impaired, or develop compensatory mechanisms. We evaluated GABAergic interneurons...

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Main Authors: Zhang, Wei, Yamawaki, Ruth, Wen, Xiling, Uhl, Justin, Diaz, Jessica, Prince, David A., Buckmaster, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802278/
https://ncbi.nlm.nih.gov/pubmed/19906972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3842-09.2009
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