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Genetic and biochemical definition of the Hedgehog receptor

Although the transporter-like protein Patched (Ptc) is genetically implicated in reception of the extracellular Hedgehog (Hh) protein signal, a clear definition of the Hh receptor is complicated by the existence of additional Hh-binding proteins and, in Drosophila, by the lack of physical evidence f...

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Autori principali: Zheng, Xiaoyan, Mann, Randall K., Sever, Navdar, Beachy, Philip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802192/
https://ncbi.nlm.nih.gov/pubmed/20048000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1870310
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