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Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form
Owing to their covalent modification by cholesterol and palmitate, Hedgehog (Hh) signaling proteins are localized predominantly to the plasma membrane of expressing cells. Yet Hh proteins are also capable of mobilizing to and eliciting direct responses from distant cells. The zebrafish you gene, ide...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387659/ https://ncbi.nlm.nih.gov/pubmed/22677548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191866.112 |
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