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C/EBPβ(ΔuORF) mice—a genetic model for uORF-mediated translational control in mammals
Upstream ORFs (uORFs) are translational control elements found predominantly in transcripts of key regulatory genes. No mammalian genetic model exists to experimentally validate the physiological relevance of uORF-regulated translation initiation. We report that mice deficient for the CCAAT/enhancer...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802187/ https://ncbi.nlm.nih.gov/pubmed/20047998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.557910 |
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