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Basis of altered RNA-binding specificity by PUF proteins revealed by crystal structures of yeast Puf4p
Pumilio/FBF (PUF) family proteins are found in eukaryotic organisms and regulate gene expression post-transcriptionally by binding to sequences in the 3′ untranslated region of target transcripts. PUF proteins contain an RNA binding domain that typically comprises eight α-helical repeats, each of wh...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802072/ https://ncbi.nlm.nih.gov/pubmed/18327269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1390 |
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