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Distinct RNA-binding modules in a single PUF protein cooperate to determine RNA specificity
PUF proteins, named for Drosophila Pumilio (PUM) and Caenorhabditis elegans fem-3-binding factor (FBF), recognize specific sequences in the mRNAs they bind and control. RNA binding by classical PUF proteins is mediated by a characteristic PUM homology domain (PUM-HD). The Puf1 and Puf2 proteins poss...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145691/ https://ncbi.nlm.nih.gov/pubmed/31294800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz583 |
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