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MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice
Spinal p38 MAP kinase plays a key role in chronic pain behavior. However, clinical development of p38 inhibitors has been hindered by significant toxicity. To evaluate alternative strategies of p38 regulation, we determined if known upstream activators of p38 (MKK3 and MKK6), are involved in develop...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802055/ https://ncbi.nlm.nih.gov/pubmed/19427893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2009.05.008 |
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