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Differential Roles of MAPK Kinases MKK3 and MKK6 in Osteoclastogenesis and Bone Loss

Bone mass is maintained by osteoclasts that resorb bone and osteoblasts that promote matrix deposition and mineralization. Bone homeostasis is altered in chronic inflammation as well as in post-menopausal loss of estrogen, which favors osteoclast activity that leads to osteoporosis. The MAPK p38α is...

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Main Authors: Boyle, David L., Hammaker, Deepa, Edgar, Meghan, Zaiss, Mario M., Teufel, Stefan, David, Jean Pierre, Schett, Georg, Firestein, Gary S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3882259/
https://ncbi.nlm.nih.gov/pubmed/24400116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084818
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